Virus Testing under GMP conditions
We provide you the possibility to test your samples for various pathogenic viruses. Virus testing can be used as an in-process control in research and for a final lot release of biological materials. With the aid of in-house developed qualitative real-time PCR systems, viruses considered as contaminations can be detected in cell cultures, cell culture supernatants, antibody formulations and other matrices. Our virus testing service includes the extraction of nucleic acids and the following qPCR. You can get further information on demand, in our service flyer or via the assay specific sections.
Attention: No testing of clinical samples! We can support you in your occupational prevention (Corona-Screening) or in ATMP production. Please contact us for further informationen.
Available Virus Testing | Overview
Human Viruses | Background
Hepatitis A virus is a picornavirus. It is non-enveloped and contains a single-stranded RNA packaged in a protein shell. There is only one serotype of the virus, but multiple genotypes exist. Characteristic of the HAV are its distinct environmental and high thermal stability and its high resistance to disinfectants. HAV is spread worldwide. The infections occur sporadically, endemically or in the form of epidemics.
Hepatitis B virus is a small, enveloped DNA virus belonging to the family of Hepadnaviridae. The genome consists of a circular, partially double stranded DNA which is synthesized by an RNA intermediate and a reverse transcriptase. The virus has a relatively high stability against environmental influences as well as a high resistance to disinfectants.
Hepatitis C virus is a linear, single-stranded, enveloped RNA virus, which has a positive strand polarity. It has a high mutation rate due to a pronounced genetic variability.
Human Immunodeficiency Virus - 1 and -2 (HIV-1 and -2)
Human immunodeficiency virus is a lymphotropic lentivirus from the family of retroviruses. Virus particles containing two RNA strands enclosed by a capsid protein and a lipid membrane with enveloping proteins. HIV is differed in HIV-1 and HIV-2 which can be also divided in different subtypes.
Parvovirus B19 (PB19)
Parvovirus B19 is a small single-stranded DNA virus belonging to the family of parvoviruses. It belongs to the genus Erythrovirus. It has a diameter of 20 to 24 nm and is one of the smallest known viruses. The virion of parvovirus B19 is characterized by a very high stability against environmental influences and detergents.
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)
The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is one of the largest single-stranded RNA viruses known to date and is assigned to the Coronaviridae family. It belongs to the genus Betacoronavirus and has a diameter of approximately 125 nm. The SARS-CoV Virion is characterized by a relatively high stability against environmental factors and detergents. It was determined that the virus can still be infectious on surfaces after 72-96 hours. The latest variant, the so-called SARS-CoV-2, was described for the first time in 2020 and currently has WHO pandemic status.